Follow up questions
1. How are then companies paid for the fee (profit) part?
2. Do you get reimbursed for the indirect cost also? For example, if we have monthly rent for the facility, do we submit an invoice for it every month to get reimbursed?
For the Gantt chart, the best spot for that in your grant would be in either in your Approach section to help visualize your proposed work throughout the grant period, or with your conclusion at the end of your proposal.
While it is indeed not required to have preliminary data available for a Phase I submission, it does greatly improve your chances of securing funding. Of course, this also varies with the type of innovation you are aiming to develop, and the feasibility of generating preliminary data for your specific innovation at this stage of development. At a minimum, you will want to have extensive literature support compiled or some proof of concept data available to support the underlying scientific premise of your innovation.