SBIR Funding Opportunities

FOA#	Topic/Title	Budget	Deadline
NOT-MH-24-110	Notice of Special Interest (NOSI): SBIR/STTR Program Priorities to Bridge Gaps in Advancing the NIMH Mission	N/A	January 6, 2027
NOT-MH-24-120	Notice of Special Interest (NOSI): SBIR/STTR High-Priority Areas for Digital Mental Health Innovations	N/A	January 6, 2027
PAR-24-066	NEI Small Business Innovation Research (SBIR) Cooperative Agreement for Early-Stage Clinical Trials with Greater than Minimal Risk (U44-Clinical Trial Required)	$2,000,000	September 23, 2026
PAS-22-196	Advancing Research on Alzheimer’s Disease (AD) and AD-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional)PHS 2022-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)	$275,766 Phase I $1,838,436 Phase II	September 5, 2025
RFA-DA-23-021	Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R43/R44 – Clinical Trial Optional)	$400,000 (Phase I); $3,000,000 (Phase II)	February 14, 2025

NOT-DE-21-012	Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed)	$259,613 for Phase I awards and $1,730,751 for Phase II awards	September 5, 2025

FOA#	TOPIC/TITLE	BUDGET	DEADLINE
	Cradle-to-Commerce (C2C)	N/A	December 20, 2024
	CDMRP Ovarian Cancer Research Program (OCRP)	$300,000-2,000,000

FOA#	TOPIC/TITLE	BUDGET	DEADLINE
	Sensor Technology for the 21st Century	varies	varies

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